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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
14.5 DPC

23 matching records from 23 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Kdr  kinase insert domain protein receptor   (Synonyms: Flk1, Flk-1, orv, vascular endothelial growth factor receptor- 2, VEGFR2, VEGFR-2, VEGF receptor-2)
Results  Reference
1J:151060 Ahlbrecht K, Schmitz J, Seay U, Schwarz C, Mittnacht-Kraus R, Gaumann A, Haberberger RV, Herold S, Breier G, Grimminger F, Seeger W, Voswinckel R, Spatiotemporal expression of flk-1 in pulmonary epithelial cells during lung development. Am J Respir Cell Mol Biol. 2008 Aug;39(2):163-70
1J:284215 Auvinen K, Lokka E, Mokkala E, Jappinen N, Tyystjarvi S, Saine H, Peurla M, Shetty S, Elima K, Rantakari P, Salmi M, Fenestral diaphragms and PLVAP associations in liver sinusoidal endothelial cells are developmentally regulated. Sci Rep. 2019 Oct 30;9(1):15698
1*J:165398 Barnes RM, Firulli BA, Conway SJ, Vincentz JW, Firulli AB, Analysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivatives. Dev Dyn. 2010 Nov;239(11):3086-97
1J:235773 Bui HM, Enis D, Robciuc MR, Nurmi HJ, Cohen J, Chen M, Yang Y, Dhillon V, Johnson K, Zhang H, Kirkpatrick R, Traxler E, Anisimov A, Alitalo K, Kahn ML, Proteolytic activation defines distinct lymphangiogenic mechanisms for VEGFC and VEGFD. J Clin Invest. 2016 Jun 1;126(6):2167-80
1*J:333561 Campbell B, Weber LM, Engle SJ, Ozolins TRS, Bourassa P, Aiello R, Liefke R, Investigation of SAMD1 ablation in mice. Sci Rep. 2023 Feb 21;13(1):3000
1J:175836 Cariboni A, Davidson K, Dozio E, Memi F, Schwarz Q, Stossi F, Parnavelas JG, Ruhrberg C, VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels. Development. 2011 Sep;138(17):3723-33
1J:222247 Duan X, Murata Y, Liu Y, Nicolae C, Olsen BR, Berendsen AD, Vegfa regulates perichondrial vascularity and osteoblast differentiation in bone development. Development. 2015 Jun 1;142(11):1984-91
1J:239361 Guimaraes-Camboa N, Stowe J, Aneas I, Sakabe N, Cattaneo P, Henderson L, Kilberg MS, Johnson RS, Chen J, McCulloch AD, Nobrega MA, Evans SM, Zambon AC, HIF1alpha Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes. Dev Cell. 2015 Jun 08;33(5):507-21
1J:333870 Jazwiec PA, Patterson VS, Ribeiro TA, Yeo E, Kennedy KM, Mathias PCF, Petrik JJ, Sloboda DM, Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism. Biol Reprod. 2022 Aug 9;107(2):574-589
1J:183083 Katz TC, Singh MK, Degenhardt K, Rivera-Feliciano J, Johnson RL, Epstein JA, Tabin CJ, Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells. Dev Cell. 2012 Mar 13;22(3):639-50
1J:170175 Kulkarni RM, Herman A, Ikegami M, Greenberg JM, Akeson AL, Lymphatic ontogeny and effect of hypoplasia in developing lung. Mech Dev. 2011 Jan-Feb;128(1-2):29-40
1J:250062 Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P, Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. BMC Biol. 2016 Mar 16;14:19
1*J:82684 Motoike T, Markham DW, Rossant J, Sato TN, Evidence for novel fate of Flk1+ progenitor: Contribution to muscle lineage. Genesis. 2003 Mar;35(3):153-9
1J:207212 Oh WJ, Gu C, Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism. Neuron. 2013 Oct 16;80(2):458-69
1*J:278094 Pu W, He L, Han X, Tian X, Li Y, Zhang H, Liu Q, Huang X, Zhang L, Wang QD, Yu Z, Yang X, Smart N, Zhou B, Genetic Targeting of Organ-Specific Blood Vessels. Circ Res. 2018 Jun 22;123(1):86-99
1J:238844 Scully KM, Skowronska-Krawczyk D, Krawczyk M, Merkurjev D, Taylor H, Livolsi A, Tollkuhn J, Stan RV, Rosenfeld MG, Epithelial cell integrin beta1 is required for developmental angiogenesis in the pituitary gland. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13408-13413
1J:314585 Shadad O, Chaulagain R, Luukko K, Kettunen P, Establishment of tooth blood supply and innervation is developmentally regulated and takes place through differential patterning processes. J Anat. 2019 Apr;234(4):465-479
1J:309164 Tian X, He L, Liu K, Pu W, Zhao H, Li Y, Liu X, Tang M, Sun R, Fei J, Ji Y, Qiao Z, Lui KO, Zhou B, Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation. EMBO J. 2020 Feb 17;39(4):e102675
1J:212075 Tian X, Hu T, Zhang H, He L, Huang X, Liu Q, Yu W, He L, Yang Z, Yan Y, Yang X, Zhong TP, Pu WT, Zhou B, Vessel formation. De novo formation of a distinct coronary vascular population in neonatal heart. Science. 2014 Jul 4;345(6192):90-4
1J:292317 Utz SG, See P, Mildenberger W, Thion MS, Silvin A, Lutz M, Ingelfinger F, Rayan NA, Lelios I, Buttgereit A, Asano K, Prabhakar S, Garel S, Becher B, Ginhoux F, Greter M, Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development. Cell. 2020 Apr 30;181(3):557-573.e18
1J:133799 van den Akker NM, Molin DG, Peters PP, Maas S, Wisse LJ, van Brempt R, van Munsteren CJ, Bartelings MM, Poelmann RE, Carmeliet P, Gittenberger-de Groot AC, Tetralogy of fallot and alterations in vascular endothelial growth factor-A signaling and notch signaling in mouse embryos solely expressing the VEGF120 isoform. Circ Res. 2007 Mar 30;100(6):842-9
1J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34
1J:193198 Wu B, Zhang Z, Lui W, Chen X, Wang Y, Chamberlain AA, Moreno-Rodriguez RA, Markwald RR, O'Rourke BP, Sharp DJ, Zheng D, Lenz J, Baldwin HS, Chang CP, Zhou B, Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling. Cell. 2012 Nov 21;151(5):1083-96

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory